I had this issue using Firefox, so I switched to IE, but I'm still having the same issue. When I am customizing a sceen, I can't scroll to the bottom where the buttons, "Publish" and "Save & Close", can be displayed so that I can click on any of them. It will show briefly and then disappear behind the bottom of the browser window. I found out that I can right click on this toolbox and select the action I want, just wasn't sure if I should be able to click on the buttons or not.
Thanks,